The LuxS/AI-2 Quorum-Sensing System of Streptococcus pneumoniae Is Required to Cause Disease, and to Regulate Virulence- and Metabolism-Related Genes in a Rat Model of Middle Ear Infection

Objective: Streptococcus pneumoniae colonizes the nasopharynx of children, and from nasopharynx it could migrate to the middle ear and causes acute otitis media (AOM). During colonization and AOM, the pneumococcus forms biofilms. In vitro biofilm formation requires a functional LuxS/AI-2 quorum-sens...

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Detalles Bibliográficos
Autores principales: Yadav, Mukesh K., Vidal, Jorge E., Go, Yoon Y., Kim, Shin H., Chae, Sung-Won, Song, Jae-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945837/
https://www.ncbi.nlm.nih.gov/pubmed/29780750
http://dx.doi.org/10.3389/fcimb.2018.00138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945837/
https://www.ncbi.nlm.nih.gov/pubmed/29780750
http://dx.doi.org/10.3389/fcimb.2018.00138

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