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Alpha-Synuclein: From Early Synaptic Dysfunction to Neurodegeneration

Over the last two decades, many experimental and clinical studies have provided solid evidence that alpha-synuclein (α-syn), a small, natively unfolded protein, is closely related to Parkinson’s disease (PD) pathology. To provide an overview on the different roles of this protein, here we propose a...

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Detalles Bibliográficos
Autores principales: Ghiglieri, Veronica, Calabrese, Valeria, Calabresi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945838/
https://www.ncbi.nlm.nih.gov/pubmed/29780350
http://dx.doi.org/10.3389/fneur.2018.00295