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P2RX7-MAPK1/2-SP1 axis inhibits MTOR independent HSPB1-mediated astroglial autophagy

Recently, we have reported that heat shock protein B1 (HSPB1) and purinergic receptor P2X7 (P2RX7) are involved in astroglial autophagy (clasmatodendrosis), following status epilepticus (SE). However, the underlying mechanisms of astroglial autophagy have not been completely established. In the pres...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Ko, Ah-Reum, Hyun, Hye-Won, Min, Su-Ji, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945848/
https://www.ncbi.nlm.nih.gov/pubmed/29749377
http://dx.doi.org/10.1038/s41419-018-0586-x