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Therapeutic Interference With Vascular Calcification—Lessons From Klotho-Hypomorphic Mice and Beyond
Medial vascular calcification, a major pathophysiological process associated with cardiovascular disease and mortality, involves osteo-/chondrogenic transdifferentiation of vascular smooth muscle cells (VSMCs). In chronic kidney disease (CKD), osteo-/chondrogenic transdifferentiation of VSMCs and, t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945862/ https://www.ncbi.nlm.nih.gov/pubmed/29780355 http://dx.doi.org/10.3389/fendo.2018.00207 |