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Regulation of Hematopoietic Cell Development and Function Through Phosphoinositides

One of the most paramount receptor-induced signal transduction mechanisms in hematopoietic cells is production of the lipid second messenger phosphatidylinositol(3,4,5)trisphosphate (PIP(3)) by class I phosphoinositide 3 kinases (PI3K). Defective PIP(3) signaling impairs almost every aspect of hemat...

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Detalles Bibliográficos
Autores principales: Elich, Mila, Sauer, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945867/
https://www.ncbi.nlm.nih.gov/pubmed/29780388
http://dx.doi.org/10.3389/fimmu.2018.00931