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Regulation of Hematopoietic Cell Development and Function Through Phosphoinositides
One of the most paramount receptor-induced signal transduction mechanisms in hematopoietic cells is production of the lipid second messenger phosphatidylinositol(3,4,5)trisphosphate (PIP(3)) by class I phosphoinositide 3 kinases (PI3K). Defective PIP(3) signaling impairs almost every aspect of hemat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945867/ https://www.ncbi.nlm.nih.gov/pubmed/29780388 http://dx.doi.org/10.3389/fimmu.2018.00931 |