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Estimation of intrathecal IgG synthesis: simulation of the risk of underestimation

OBJECTIVE: The low level of passively diffused IgG through the blood–brain barrier is sufficient to blur the estimation of intrathecal IgG synthesis (ITS). Therefore, this estimation requires a mathematical calculation derived from empirical laws, but the range of normal values in healthy controls i...

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Detalles Bibliográficos
Autores principales: Bonnan, Mickael, Gianoli‐Guillerme, Mariana, Courtade, Henri, Demasles, Stéphanie, Krim, Elsa, Marasescu, Raluca, Dréau, Hervé, Debeugny, Stéphane, Barroso, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945966/
https://www.ncbi.nlm.nih.gov/pubmed/29761116
http://dx.doi.org/10.1002/acn3.548