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Myeloperoxidase Negatively Regulates Neutrophil–Endothelial Cell Interactions by Impairing αMβ2 Integrin Function in Sterile Inflammation

Interactions of neutrophils with endothelial cells (ECs) and platelets contribute to tissue damage and vascular occlusion under sterile inflammatory conditions. However, the molecular mechanisms regulating the cell–cell interactions remain poorly understood. Previous studies suggest that reactive ox...

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Detalles Bibliográficos
Autores principales: Tseng, Alan, Kim, Kyungho, Li, Jing, Cho, Jaehyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946029/
https://www.ncbi.nlm.nih.gov/pubmed/29780806
http://dx.doi.org/10.3389/fmed.2018.00134