The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway

Oncogenic signals lead to premature senescence in normal human cells causing a proliferation arrest and the elimination of these defective cells by immune cells. Oncogene‐induced senescence (OIS) prevents aberrant cell division and tumor initiation. In order to identify new regulators of OIS, we per...

Descripción completa

Detalles Bibliográficos
Autores principales: Warnier, Marine, Flaman, Jean‐Michel, Chouabe, Christophe, Wiel, Clotilde, Gras, Baptiste, Griveau, Audrey, Blanc, Elena, Foy, Jean‐Philippe, Mathot, Pauline, Saintigny, Pierre, Van Coppenolle, Fabien, Vindrieux, David, Martin, Nadine, Bernard, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946064/
https://www.ncbi.nlm.nih.gov/pubmed/29446526
http://dx.doi.org/10.1111/acel.12736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946064/
https://www.ncbi.nlm.nih.gov/pubmed/29446526
http://dx.doi.org/10.1111/acel.12736

Ejemplares similares