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The mitochondrial unfolded protein response is activated upon hematopoietic stem cell exit from quiescence

The mitochondrial unfolded protein response (UPR (mt)), a cellular protective program that ensures proteostasis in the mitochondria, has recently emerged as a regulatory mechanism for adult stem cell maintenance that is conserved across tissues. Despite the emerging genetic evidence implicating the...

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Detalles Bibliográficos
Autores principales: Mohrin, Mary, Widjaja, Andrew, Liu, Yufei, Luo, Hanzhi, Chen, Danica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946069/
https://www.ncbi.nlm.nih.gov/pubmed/29575576
http://dx.doi.org/10.1111/acel.12756