Evidence that miR‐146a attenuates aging‐ and trauma‐induced osteoarthritis by inhibiting Notch1, IL‐6, and IL‐1 mediated catabolism

Primary osteoarthritis (OA) is associated with aging, while post‐traumatic OA (PTOA) is associated with mechanical injury and inflammation. It is not clear whether the two types of osteoarthritis share common mechanisms. We found that miR‐146a, a microRNA‐associated with inflammation, is activated b...

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Detalles Bibliográficos
Autores principales: Guan, Ying‐Jie, Li, Jing, Yang, Xu, Du, Shaohua, Ding, Jing, Gao, Yun, Zhang, Ying, Yang, Kun, Chen, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946074/
https://www.ncbi.nlm.nih.gov/pubmed/29575548
http://dx.doi.org/10.1111/acel.12752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946074/
https://www.ncbi.nlm.nih.gov/pubmed/29575548
http://dx.doi.org/10.1111/acel.12752

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