Evidence that miR‐146a attenuates aging‐ and trauma‐induced osteoarthritis by inhibiting Notch1, IL‐6, and IL‐1 mediated catabolism

Primary osteoarthritis (OA) is associated with aging, while post‐traumatic OA (PTOA) is associated with mechanical injury and inflammation. It is not clear whether the two types of osteoarthritis share common mechanisms. We found that miR‐146a, a microRNA‐associated with inflammation, is activated b...

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Bibliografiska uppgifter
Huvudupphovsmän: Guan, Ying‐Jie, Li, Jing, Yang, Xu, Du, Shaohua, Ding, Jing, Gao, Yun, Zhang, Ying, Yang, Kun, Chen, Qian
Materialtyp: Online Artikel Text
Språk:English
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Original Articles
Länkar:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946074/
https://www.ncbi.nlm.nih.gov/pubmed/29575548
http://dx.doi.org/10.1111/acel.12752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946074/
https://www.ncbi.nlm.nih.gov/pubmed/29575548
http://dx.doi.org/10.1111/acel.12752

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