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The effects of graded caloric restriction: XII. Comparison of mouse to human impact on cellular senescence in the colon

Calorie restriction (CR) is an effective strategy to delay the onset and progression of aging phenotypes in a variety of organisms. Several molecular players are involved in the anti‐aging effects of CR, but mechanisms of regulation are poorly understood. Cellular senescence—a cellular state of irre...

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Detalles Bibliográficos
Autores principales: Fontana, Luigi, Mitchell, Sharon E., Wang, Boshi, Tosti, Valeria, van Vliet, Thijmen, Veronese, Nicola, Bertozzi, Beatrice, Early, Dayna S., Maissan, Parcival, Speakman, John R., Demaria, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946078/
https://www.ncbi.nlm.nih.gov/pubmed/29575469
http://dx.doi.org/10.1111/acel.12746