Local delivery of tetramethylpyrazine eliminates the senescent phenotype of bone marrow mesenchymal stromal cells and creates an anti‐inflammatory and angiogenic environment in aging mice

Aging drives the accumulation of senescent cells (SnCs) including stem/progenitor cells in bone marrow, which contributes to aging‐related bone degenerative pathologies. Local elimination of SnCs has been shown as potential treatment for degenerative diseases. As LepR(+) mesenchymal stem/progenitor...

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Detalles Bibliográficos
Autores principales: Gao, Bo, Lin, Xisheng, Jing, Huan, Fan, Jing, Ji, Chenchen, Jie, Qiang, Zheng, Chao, Wang, Di, Xu, Xiaolong, Hu, Yaqian, Lu, Weiguang, Luo, Zhuojing, Yang, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946084/
https://www.ncbi.nlm.nih.gov/pubmed/29488314
http://dx.doi.org/10.1111/acel.12741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946084/
https://www.ncbi.nlm.nih.gov/pubmed/29488314
http://dx.doi.org/10.1111/acel.12741

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