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Aging impacts CD103(+) CD8(+) T cell presence and induction by dendritic cells in the genital tract

As women age, susceptibility to systemic and genital infections increases. Tissue‐resident memory T cells (TRMs) are CD103(+) CD8(+) long‐lived lymphocytes that provide critical mucosal immune protection. Mucosal dendritic cells (DCs) are known to induce CD103 expression on CD8(+) T cells. While CD1...

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Detalles Bibliográficos
Autores principales: Rodriguez‐Garcia, Marta, Fortier, Jared M., Barr, Fiona D., Wira, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946085/
https://www.ncbi.nlm.nih.gov/pubmed/29455474
http://dx.doi.org/10.1111/acel.12733