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Vascular smooth muscle cells direct extracellular dysregulation in aortic stiffening of hypertensive rats

Aortic stiffening is an independent risk factor that underlies cardiovascular morbidity in the elderly. We have previously shown that intrinsic mechanical properties of vascular smooth muscle cells (VSMCs) play a key role in aortic stiffening in both aging and hypertension. Here, we test the hypothe...

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Detalles Bibliográficos
Autores principales: Hays, Tristan T., Ma, Ben, Zhou, Ning, Stoll, Shaunrick, Pearce, William J., Qiu, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946086/
https://www.ncbi.nlm.nih.gov/pubmed/29603864
http://dx.doi.org/10.1111/acel.12748