Cargando…

Vascular smooth muscle cells direct extracellular dysregulation in aortic stiffening of hypertensive rats

Aortic stiffening is an independent risk factor that underlies cardiovascular morbidity in the elderly. We have previously shown that intrinsic mechanical properties of vascular smooth muscle cells (VSMCs) play a key role in aortic stiffening in both aging and hypertension. Here, we test the hypothe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hays, Tristan T., Ma, Ben, Zhou, Ning, Stoll, Shaunrick, Pearce, William J., Qiu, Hongyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946086/ https://www.ncbi.nlm.nih.gov/pubmed/29603864 http://dx.doi.org/10.1111/acel.12748

Ejemplares similares

Inhibition of SRF/myocardin reduces aortic stiffness by targeting vascular smooth muscle cell stiffening in hypertension
por: Zhou, Ning, et al.
Publicado: (2017)

Rho Kinase Regulates Aortic Vascular Smooth Muscle Cell Stiffness Via Actin/SRF/Myocardin in Hypertension
por: Zhou, Ning, et al.
Publicado: (2017)

The valosin‐containing protein is a novel repressor of cardiomyocyte hypertrophy induced by pressure overload
por: Zhou, Ning, et al.
Publicado: (2017)

DNA Methylation and Histone Modification in Hypertension
por: Stoll, Shaunrick, et al.
Publicado: (2018)

Smoking and Female Sex: Independent Predictors of Human Vascular Smooth Muscle Cells Stiffening
por: Dinardo, Carla Luana, et al.
Publicado: (2015)

VCP represses pathological cardiac hypertrophy
por: Zhou, Ning, et al.
Publicado: (2017)

Interleukin-1β in Multifactorial Hypertension: Inflammation, Vascular Smooth Muscle Cell and Extracellular Matrix Remodeling, and Non-Coding RNA Regulation
por: Melton, Elaina, et al.
Publicado: (2021)

Apelin expression deficiency in mice contributes to vascular stiffening by extracellular matrix remodeling of the aortic wall
por: Romier, Beatrice, et al.
Publicado: (2021)

Vascular smooth muscle contraction in hypertension
por: Touyz, Rhian M, et al.
Publicado: (2018)

The valosin-containing protein is a novel mediator of mitochondrial respiration and cell survival in the heart in vivo
por: Lizano, Paulo, et al.
Publicado: (2017)

Age-Associated Dysregulation of Integrin Function in Vascular Smooth Muscle
por: Ojha, Krishna Raj, et al.
Publicado: (2022)

Functional Inhibition of Valosin-Containing Protein Induces Cardiac Dilation and Dysfunction in a New Dominant-Negative Transgenic Mouse Model
por: Sun, Xiaonan, et al.
Publicado: (2021)

Characterization of Contractile Machinery of Vascular Smooth Muscles in Hypertension
por: Yang, Qunhui, et al.
Publicado: (2021)

Vascular smooth muscle ion channels in essential hypertension
por: Daghbouche-Rubio, Nuria, et al.
Publicado: (2022)

Premature aortic smooth muscle cell differentiation contributes to matrix dysregulation in Marfan Syndrome
por: Dale, Matthew, et al.
Publicado: (2017)

Vascular stiffening and endothelial dysfunction in atherosclerosis
por: Hooglugt, Aukie, et al.
Publicado: (2022)

Increasing pulse pressure ex vivo, mimicking acute physical exercise, induces smooth muscle cell-mediated de-stiffening of murine aortic segments
por: Neutel, Cédric H. G., et al.
Publicado: (2023)

Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II–Induced Hypertension
por: Fry, Jessica L, et al.
Publicado: (2015)

Cholesterol Efflux: Does It Contribute to Aortic Stiffening?
por: Liao, Shutan, et al.
Publicado: (2018)

Novel genomic targets of valosin-containing protein in protecting pathological cardiac hypertrophy
por: Zhou, Ning, et al.
Publicado: (2020)

Genomic characterization reveals novel mechanisms underlying the valosin-containing protein-mediated cardiac protection against heart failure
por: Zhou, Ning, et al.
Publicado: (2020)

Inhibition of Aortic Intimal Hyperplasia and Vascular Smooth Muscle Proliferation and Extracellular Matrix Protein Expressions by Astragalus–Angelica Combination
por: Yan, Huifang, et al.
Publicado: (2018)

Correction: Premature aortic smooth muscle cell differentiation contributes to matrix dysregulation in Marfan Syndrome
por: Dale, Matthew, et al.
Publicado: (2018)

Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms
por: Clément, Marc, et al.
Publicado: (2019)

Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms
por: Lu, Haocheng, et al.
Publicado: (2021)

The role of vascular smooth muscle cells in the development of aortic aneurysms and dissections
por: Rombouts, Karlijn B., et al.
Publicado: (2021)

Engineering Smooth Muscle to Understand Extracellular Matrix Remodeling and Vascular Disease
por: Yarbrough, Danielle, et al.
Publicado: (2022)

miR‐145 attenuates phenotypic transformation of aortic vascular smooth muscle cells to prevent aortic dissection
por: Qiu, Zhi‐Huang, et al.
Publicado: (2021)

Age and hypertension strongly induce aortic stiffening in rats at basal and matched blood pressure levels
por: Lindesay, George, et al.
Publicado: (2016)

Age-related vascular stiffening: causes and consequences
por: Kohn, Julie C., et al.
Publicado: (2015)

Polycystin-1 Downregulation Induced Vascular Smooth Muscle Cells Phenotypic Alteration and Extracellular Matrix Remodeling in Thoracic Aortic Dissection
por: Zhang, Jing, et al.
Publicado: (2020)

Dysregulation of interaction between LOX(high) fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection
por: Chen, Yinan, et al.
Publicado: (2022)

Effect of miRNA-218-5p on Proliferation, Migration, Apoptosis and Inflammation of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm and Extracellular Matrix Protein
por: Hu, Min, et al.
Publicado: (2022)

The Contribution of Extracellular Vesicles From Senescent Endothelial and Vascular Smooth Muscle Cells to Vascular Calcification
por: Mas-Bargues, Cristina, et al.
Publicado: (2022)

Crosslinked Extracellular Matrix Stiffens Human Trabecular Meshwork Cells Via Dysregulating β-catenin and YAP/TAZ Signaling Pathways
por: Yemanyi, Felix, et al.
Publicado: (2020)

Abdominal Aortic Aneurysm Formation with a Focus on Vascular Smooth Muscle Cells
por: Qian, Guoqing, et al.
Publicado: (2022)

BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension
por: Chen, Dan, et al.
Publicado: (2019)

Dynamic Crosstalk between Vascular Smooth Muscle Cells and the Aged Extracellular Matrix
por: Ribeiro-Silva, Joao Carlos, et al.
Publicado: (2021)

Extracellular Vesicles Mediate Communication between Endothelial and Vascular Smooth Muscle Cells
por: Fontaine, Marie, et al.
Publicado: (2021)

Paradigms of endothelial stiffening in cardiovascular disease and vascular aging
por: Aguilar, Victor M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lu0cfvbum90ao8pv5qj074alj2