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High Glucose-Mediated Tyrosine Nitration of PI3-Kinase: A Molecular Switch of Survival and Apoptosis in Endothelial Cells

Diabetes and hyperglycemia are associated with increased retinal oxidative and nitrative stress and vascular cell death. Paradoxically, high glucose stimulates expression of survival and angiogenic growth factors. Therefore, we examined the hypothesis that high glucose-mediated tyrosine nitration ca...

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Detalles Bibliográficos
Autores principales: Elshaer, Sally L., Lemtalsi, Tahira, El-Remessy, Azza B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946113/
https://www.ncbi.nlm.nih.gov/pubmed/29587384
http://dx.doi.org/10.3390/antiox7040047