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Reactive glia promote development of CD103(+)CD69(+) CD8(+) T‐cells through programmed cell death‐ligand 1 (PD‐L1)

INTRODUCTION: Previous work from our laboratory has demonstrated in vivo persistence of CD103(+)CD69(+) brain resident memory CD8(+) T‐cells (bT(RM)) following viral infection, and that the PD‐1: PD‐L1 pathway promotes development of these T(RM) cells within the brain. Although glial cells express l...

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Detalles Bibliográficos
Autores principales: Prasad, Sujata, Hu, Shuxian, Sheng, Wen S., Chauhan, Priyanka, Lokensgard, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946148/
https://www.ncbi.nlm.nih.gov/pubmed/29602245
http://dx.doi.org/10.1002/iid3.221