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Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells

INTRODUCTION: Impaired proliferation and production of IL2 are the hallmarks of experimental T cell tolerance. However, in most autoimmune diseases, auto‐reactive T cells do not display hyper proliferation, but inflammatory phenotypes. METHODS: We have now demonstrated that the transcription factors...

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Detalles Bibliográficos
Autores principales: Omodho, Becky, Miao, Tizong, Symonds, Alistair L.J., Singh, Randeep, Li, Suling, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946152/
https://www.ncbi.nlm.nih.gov/pubmed/29314730
http://dx.doi.org/10.1002/iid3.210