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ASF1 is required to load histones on the HIRA complex in preparation of paternal chromatin assembly at fertilization
BACKGROUND: Anti-Silencing Factor 1 (ASF1) is a conserved H3–H4 histone chaperone involved in both Replication-Coupled and Replication-Independent (RI) nucleosome assembly pathways. At DNA replication forks, ASF1 plays an important role in regulating the supply of H3.1/2 and H4 to the CAF-1 chromati...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946387/ https://www.ncbi.nlm.nih.gov/pubmed/29751847 http://dx.doi.org/10.1186/s13072-018-0189-x |