Cargando…
ASF1 is required to load histones on the HIRA complex in preparation of paternal chromatin assembly at fertilization
BACKGROUND: Anti-Silencing Factor 1 (ASF1) is a conserved H3–H4 histone chaperone involved in both Replication-Coupled and Replication-Independent (RI) nucleosome assembly pathways. At DNA replication forks, ASF1 plays an important role in regulating the supply of H3.1/2 and H4 to the CAF-1 chromati...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946387/ https://www.ncbi.nlm.nih.gov/pubmed/29751847 http://dx.doi.org/10.1186/s13072-018-0189-x |