Cargando…

BCL-2 as therapeutic target for hematological malignancies

Disruption of the physiologic balance between cell proliferation and cell death is an important step of cancer development. Increased resistance to apoptosis is a key oncogenic mechanism in several hematological malignancies and, in many cases, especially in lymphoid neoplasias, has been attributed...

Descripción completa

Detalles Bibliográficos
Autores principales: Perini, Guilherme Fleury, Ribeiro, Glaciano Nogueira, Pinto Neto, Jorge Vaz, Campos, Laura Tojeiro, Hamerschlak, Nelson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946445/
https://www.ncbi.nlm.nih.gov/pubmed/29747654
http://dx.doi.org/10.1186/s13045-018-0608-2