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Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors

The structural and functional plasticity of synapses is critical for learning and memory. Long-term potentiation (LTP) induction promotes spine growth and AMPAR accumulation at excitatory synapses, leading to increased synaptic strength. Glutamate initiates these processes, but the contribution from...

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Detalles Bibliográficos
Autores principales: McLeod, Faye, Bossio, Alessandro, Marzo, Aude, Ciani, Lorenza, Sibilla, Sara, Hannan, Saad, Wilson, Gemma A., Palomer, Ernest, Smart, Trevor G., Gibb, Alasdair, Salinas, Patricia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946458/
https://www.ncbi.nlm.nih.gov/pubmed/29694885
http://dx.doi.org/10.1016/j.celrep.2018.03.119