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Infection Reveals a Modification of SIRT2 Critical for Chromatin Association

Sirtuin 2 is a nicotinamide-adenine-dinucleotide-dependent deacetylase that regulates cell processes such as carcinogenesis, cell cycle, DNA damage, and infection. Subcellular localization of SIRT2 is crucial for its function but is poorly understood. Infection with the bacterial pathogen Listeria m...

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Detalles Bibliográficos
Autores principales: Pereira, Jorge M., Chevalier, Christine, Chaze, Thibault, Gianetto, Quentin, Impens, Francis, Matondo, Mariette, Cossart, Pascale, Hamon, Mélanie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946459/
https://www.ncbi.nlm.nih.gov/pubmed/29694890
http://dx.doi.org/10.1016/j.celrep.2018.03.116