The biology and role of CD44 in cancer progression: therapeutic implications

CD44, a non-kinase transmembrane glycoprotein, is overexpressed in several cell types including cancer stem cells and frequently shows alternative spliced variants that are thought to play a role in cancer development and progression. Hyaluronan, the main ligand for CD44, binds to and activates CD44...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Zhao, Shujie, Karnad, Anand, Freeman, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946470/
https://www.ncbi.nlm.nih.gov/pubmed/29747682
http://dx.doi.org/10.1186/s13045-018-0605-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946470/
https://www.ncbi.nlm.nih.gov/pubmed/29747682
http://dx.doi.org/10.1186/s13045-018-0605-5

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