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MicroRNA 21a-5p overexpression impacts mediators of extracellular matrix formation in uterine leiomyoma

BACKGROUND: MicroRNAs (MiR) may promote fibroid development via altered expression of genes involved in cell proliferation and ECM formation, and evidence supports aberrant expression of MicroRNA (MiR) 21a-5p in fibroids. The purpose of this study was to investigate the functional significance of Mi...

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Detalles Bibliográficos
Autores principales: Cardozo, Eden R., Foster, Rosemary, Karmon, Anatte E., Lee, Amy E., Gatune, Leah W., Rueda, Bo R., Styer, Aaron K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946472/
https://www.ncbi.nlm.nih.gov/pubmed/29747655
http://dx.doi.org/10.1186/s12958-018-0364-8