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Survival of rats bearing advanced intracerebral F 98 tumors after glutathione depletion and microbeam radiation therapy: conclusions from a pilot project

BACKGROUND: Resistance to radiotherapy is frequently encountered in patients with glioblastoma multiforme. It is caused at least partially by the high glutathione content in the tumour tissue. Therefore, the administration of the glutathione synthesis inhibitor Buthionine-SR-Sulfoximine (BSO) should...

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Detalles Bibliográficos
Autores principales: Schültke, E., Bräuer-Krisch, E., Blattmann, H., Requardt, H., Laissue, J. A., Hildebrandt, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946497/
https://www.ncbi.nlm.nih.gov/pubmed/29747666
http://dx.doi.org/10.1186/s13014-018-1038-6