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Survival of rats bearing advanced intracerebral F 98 tumors after glutathione depletion and microbeam radiation therapy: conclusions from a pilot project
BACKGROUND: Resistance to radiotherapy is frequently encountered in patients with glioblastoma multiforme. It is caused at least partially by the high glutathione content in the tumour tissue. Therefore, the administration of the glutathione synthesis inhibitor Buthionine-SR-Sulfoximine (BSO) should...
Autores principales: | Schültke, E., Bräuer-Krisch, E., Blattmann, H., Requardt, H., Laissue, J. A., Hildebrandt, G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946497/ https://www.ncbi.nlm.nih.gov/pubmed/29747666 http://dx.doi.org/10.1186/s13014-018-1038-6 |
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