Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing

Peptide nucleic acids (PNAs) can bind duplex DNA in a sequence-targeted manner, forming a triplex structure capable of inducing DNA repair and producing specific genome modifications. Since the first description of PNA-mediated gene editing in cell free extracts, PNAs have been used to successfully...

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Detalles Bibliográficos
Autores principales: Ricciardi, Adele S., Quijano, Elias, Putman, Rachael, Saltzman, W. Mark, Glazer, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946696/
https://www.ncbi.nlm.nih.gov/pubmed/29534473
http://dx.doi.org/10.3390/molecules23030632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946696/
https://www.ncbi.nlm.nih.gov/pubmed/29534473
http://dx.doi.org/10.3390/molecules23030632

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