let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration

Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor cells with stem cell characteristics. This necessity for retina regeneration is often compromised in mammals. We explored the significance of developmentally inevitable Sonic hedgehog signaling and found its ne...

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Detalles Bibliográficos
Autores principales: Kaur, Simran, Gupta, Shivangi, Chaudhary, Mansi, Khursheed, Mohammad Anwar, Mitra, Soumitra, Kurup, Akshai Janardhana, Ramachandran, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946716/
https://www.ncbi.nlm.nih.gov/pubmed/29719254
http://dx.doi.org/10.1016/j.celrep.2018.04.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946716/
https://www.ncbi.nlm.nih.gov/pubmed/29719254
http://dx.doi.org/10.1016/j.celrep.2018.04.002

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