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High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia

Aging is associated with tissue-level changes in cellular composition that are correlated with increased susceptibility to disease. Aging human mammary tissue shows skewed progenitor cell potency, resulting in diminished tumor-suppressive cell types and the accumulation of defective epithelial proge...

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Detalles Bibliográficos
Autores principales: Pelissier Vatter, Fanny A., Schapiro, Denis, Chang, Hang, Borowsky, Alexander D., Lee, Jonathan K., Parvin, Bahram, Stampfer, Martha R., LaBarge, Mark A., Bodenmiller, Bernd, Lorens, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946804/
https://www.ncbi.nlm.nih.gov/pubmed/29694896
http://dx.doi.org/10.1016/j.celrep.2018.03.114