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High-Dimensional Phenotyping Identifies Age-Emergent Cells in Human Mammary Epithelia
Aging is associated with tissue-level changes in cellular composition that are correlated with increased susceptibility to disease. Aging human mammary tissue shows skewed progenitor cell potency, resulting in diminished tumor-suppressive cell types and the accumulation of defective epithelial proge...
Autores principales: | Pelissier Vatter, Fanny A., Schapiro, Denis, Chang, Hang, Borowsky, Alexander D., Lee, Jonathan K., Parvin, Bahram, Stampfer, Martha R., LaBarge, Mark A., Bodenmiller, Bernd, Lorens, James B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946804/ https://www.ncbi.nlm.nih.gov/pubmed/29694896 http://dx.doi.org/10.1016/j.celrep.2018.03.114 |
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