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Cell type discovery using single-cell transcriptomics: implications for ontological representation

Cells are fundamental function units of multicellular organisms, with different cell types playing distinct physiological roles in the body. The recent advent of single-cell transcriptional profiling using RNA sequencing is producing ‘big data’, enabling the identification of novel human cell types...

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Detalles Bibliográficos
Autores principales: Aevermann, Brian D, Novotny, Mark, Bakken, Trygve, Miller, Jeremy A, Diehl, Alexander D, Osumi-Sutherland, David, Lasken, Roger S, Lein, Ed S, Scheuermann, Richard H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946857/
https://www.ncbi.nlm.nih.gov/pubmed/29590361
http://dx.doi.org/10.1093/hmg/ddy100