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A Blood RNA Signature Detecting Severe Disease in Young Dengue Patients at Hospital Arrival

BACKGROUND: Early detection of severe dengue can improve patient care and survival. To date, no reliable single-gene biomarker exists. We hypothesized that robust multigene signatures exist. METHODS: We performed a prospective study on Cambodian dengue patients aged 4 to 22 years. Peripheral blood m...

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Detalles Bibliográficos
Autores principales: Nikolayeva, Iryna, Bost, Pierre, Casademont, Isabelle, Duong, Veasna, Koeth, Fanny, Prot, Matthieu, Czerwinska, Urszula, Ly, Sowath, Bleakley, Kevin, Cantaert, Tineke, Dussart, Philippe, Buchy, Philippe, Simon-Lorière, Etienne, Sakuntabhai, Anavaj, Schwikowski, Benno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946912/
https://www.ncbi.nlm.nih.gov/pubmed/29490079
http://dx.doi.org/10.1093/infdis/jiy086