OncoSimulR: genetic simulation with arbitrary epistasis and mutator genes in asexual populations

SUMMARY: OncoSimulR implements forward-time genetic simulations of biallelic loci in asexual populations with special focus on cancer progression. Fitness can be defined as an arbitrary function of genetic interactions between multiple genes or modules of genes, including epistasis, restrictions in...

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Detalles Bibliográficos
Autor principal: Diaz-Uriarte, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946943/
https://www.ncbi.nlm.nih.gov/pubmed/28186227
http://dx.doi.org/10.1093/bioinformatics/btx077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946943/
https://www.ncbi.nlm.nih.gov/pubmed/28186227
http://dx.doi.org/10.1093/bioinformatics/btx077

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