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Naloxegol hydrogen oxalate displaying a hydrogen-bonded layer structure

In the salt (5α,6α)-6-[(2,5,8,11,14,17,20-hepta­oxadocosan-22-yl)­oxy]-3,14-dihy­droxy-17-(prop-2-en-1-yl)-4,5-ep­oxy­morphinan-17-ium hydrogen oxalate, C(34)H(54)NO(11) (+)·C(2)HO(4) (−) the polyether unit of the naloxegol cation adopts the shape of a squashed open letter ‘O’. In the crystal, the h...

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Detalles Bibliográficos
Autores principales: Gelbrich, Thomas, Langes, Christoph, Stefinovic, Marijan, Griesser, Ulrich J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946971/
https://www.ncbi.nlm.nih.gov/pubmed/29765749
http://dx.doi.org/10.1107/S2056989018003675