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Naloxegol hydrogen oxalate displaying a hydrogen-bonded layer structure
In the salt (5α,6α)-6-[(2,5,8,11,14,17,20-heptaoxadocosan-22-yl)oxy]-3,14-dihydroxy-17-(prop-2-en-1-yl)-4,5-epoxymorphinan-17-ium hydrogen oxalate, C(34)H(54)NO(11) (+)·C(2)HO(4) (−) the polyether unit of the naloxegol cation adopts the shape of a squashed open letter ‘O’. In the crystal, the h...
Autores principales: | Gelbrich, Thomas, Langes, Christoph, Stefinovic, Marijan, Griesser, Ulrich J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946971/ https://www.ncbi.nlm.nih.gov/pubmed/29765749 http://dx.doi.org/10.1107/S2056989018003675 |
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