Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1‐linked amyotrophic lateral sclerosis mice

Cystatin C (CysC) is a major protein component of Bunina bodies, which are a pathological hallmark observed in the remaining motor neurons of patients with amyotrophic lateral sclerosis (ALS). Dominant mutations in the SOD1 gene, encoding Cu/Zn superoxide dismutase (SOD1), are causative for a subset...

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Detalles Bibliográficos
Autores principales: Watanabe, Seiji, Komine, Okiru, Endo, Fumito, Wakasugi, Keisuke, Yamanaka, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947136/
https://www.ncbi.nlm.nih.gov/pubmed/29282717
http://dx.doi.org/10.1111/jnc.14285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947136/
https://www.ncbi.nlm.nih.gov/pubmed/29282717
http://dx.doi.org/10.1111/jnc.14285

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