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Oral myeloid cells uptake allergoids coupled to mannan driving Th1/Treg responses upon sublingual delivery in mice

BACKGROUND: Polymerized allergoids coupled to nonoxidized mannan (PM‐allergoids) may represent novel vaccines targeting dendritic cells (DCs). PM‐allergoids are better captured by DCs than native allergens and favor Th1/Treg cell responses upon subcutaneous injection. Herein we have studied in mice...

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Detalles Bibliográficos
Autores principales: Soria, I., López‐Relaño, J., Viñuela, M., Tudela, J.‐I., Angelina, A., Benito‐Villalvilla, C., Díez‐Rivero, C. M., Cases, B., Manzano, A. I., Fernández‐Caldas, E., Casanovas, M., Palomares, O., Subiza, J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947296/
https://www.ncbi.nlm.nih.gov/pubmed/29319882
http://dx.doi.org/10.1111/all.13396