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Potent inhibition of miR-27a by neomycin–bisbenzimidazole conjugates

miRNAs are important components of regulatory networks that control gene expression and have implications in various diseases including cancer. Targeting oncogenic miRNAs with small molecules is currently being explored to develop cancer therapeutics. Here, we report the development of dual binding...

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Detalles Bibliográficos
Autores principales: Nahar, Smita, Ranjan, Nihar, Ray, Arjun, Arya, Dev P., Maiti, Souvik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947510/
https://www.ncbi.nlm.nih.gov/pubmed/29861909
http://dx.doi.org/10.1039/c5sc01969a