Sulfasalazine‐Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus

Agranulocytosis is a serious, although rare, adverse reaction to sulfasalazine, which is used to treat inflammatory joint and bowel disease. We performed a genome‐wide association study comprising 9,380,034 polymorphisms and 180 HLA alleles in 36 cases of sulfasalazine‐induced agranulocytosis and 5,...

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Detalles Bibliográficos
Autores principales: Wadelius, Mia, Eriksson, Niclas, Kreutz, Reinhold, Bondon‐Guitton, Emmanuelle, Ibañez, Luisa, Carvajal, Alfonso, Lucena, M. Isabel, Sancho Ponce, Esther, Molokhia, Mariam, Martin, Javier, Axelsson, Tomas, Kohnke, Hugo, Yue, Qun‐Ying, Magnusson, Patrik K.E., Bengtsson, Mats, Hallberg, Pär
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947520/
https://www.ncbi.nlm.nih.gov/pubmed/28762467
http://dx.doi.org/10.1002/cpt.805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947520/
https://www.ncbi.nlm.nih.gov/pubmed/28762467
http://dx.doi.org/10.1002/cpt.805

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