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A labelled-ubiquicidin antimicrobial peptide for immediate in situ optical detection of live bacteria in human alveolar lung tissue

The in situ immediate detection of the presence of bacteria in the distal human lung is of significant clinical utility. Herein we describe the development and optimization of a bacterial binding fragment (UBI(29–41)) of the antimicrobial peptide, ubiquicidin (UBI), conjugated to an environmentally...

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Detalles Bibliográficos
Autores principales: Akram, Ahsan R., Avlonitis, Nicolaos, Lilienkampf, Annamaria, Perez-Lopez, Ana M., McDonald, Neil, Chankeshwara, Sunay V., Scholefield, Emma, Haslett, Christopher, Bradley, Mark, Dhaliwal, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947527/
https://www.ncbi.nlm.nih.gov/pubmed/29861935
http://dx.doi.org/10.1039/c5sc00960j