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The C‐terminal cytosolic domain of the human zinc transporter ZnT8 and its diabetes risk variant

A significant aspect of the control of cellular zinc in eukarya is its subcellular re‐distribution. One of the four human vesicular zinc transporters, ZnT8, supplies the millimolar zinc concentrations of insulin granules in pancreatic β‐cells, affecting insulin processing, crystallisation and secret...

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Detalles Bibliográficos
Autores principales: Parsons, Douglas S., Hogstrand, Christer, Maret, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947572/
https://www.ncbi.nlm.nih.gov/pubmed/29430817
http://dx.doi.org/10.1111/febs.14402