Cargando…
The C‐terminal cytosolic domain of the human zinc transporter ZnT8 and its diabetes risk variant
A significant aspect of the control of cellular zinc in eukarya is its subcellular re‐distribution. One of the four human vesicular zinc transporters, ZnT8, supplies the millimolar zinc concentrations of insulin granules in pancreatic β‐cells, affecting insulin processing, crystallisation and secret...
Autores principales: | Parsons, Douglas S., Hogstrand, Christer, Maret, Wolfgang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947572/ https://www.ncbi.nlm.nih.gov/pubmed/29430817 http://dx.doi.org/10.1111/febs.14402 |
Ejemplares similares
-
ZnT8 Haploinsufficiency Impacts MIN6 Cell Zinc Content and β-Cell Phenotype via ZIP-ZnT8 Coregulation
por: Lawson, Rebecca, et al.
Publicado: (2019) -
Probing the Structure and Function of the Cytosolic Domain of the Human Zinc Transporter ZnT8 with Nickel(II) Ions
por: Catapano, Maria Carmen, et al.
Publicado: (2021) -
Zinc transporter 8 (ZnT8) autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant proteins in specific ZnT8R and ZnT8W autoantibody-positive type 1 diabetes patients
por: Skärstrand, H, et al.
Publicado: (2015) -
Insights into the Dynamics of the Human Zinc Transporter
ZnT8 by MD Simulations
por: Sala, Davide, et al.
Publicado: (2021) -
Heterologous Expression and Biochemical Characterization of the Human Zinc Transporter 1 (ZnT1) and Its Soluble C-Terminal Domain
por: Cotrim, Camila A., et al.
Publicado: (2021)