Analysis of (13)C and (14)C labeling in pyruvate and lactate in tumor and blood of lymphoma‐bearing mice injected with (13)C‐ and (14)C‐labeled pyruvate

Measurements of hyperpolarized (13)C label exchange between injected [1‐(13)C]pyruvate and the endogenous tumor lactate pool can give an apparent first‐order rate constant for the exchange. The determination of the isotope flux, however, requires an estimate of the labeled pyruvate concentration in...

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Detalles Bibliográficos
Autores principales: Serrao, E.M., Kettunen, M.I., Rodrigues, T.B., Lewis, D.Y., Gallagher, F.A., Hu, D.E., Brindle, K.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947589/
https://www.ncbi.nlm.nih.gov/pubmed/29457661
http://dx.doi.org/10.1002/nbm.3901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947589/
https://www.ncbi.nlm.nih.gov/pubmed/29457661
http://dx.doi.org/10.1002/nbm.3901

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