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Differential contributions of Ca(2+)‐activated K(+) channels and Na(+)/K(+)‐ATPases to the generation of the slow afterhyperpolarization in CA1 pyramidal cells

In many types of CNS neurons, repetitive spiking produces a slow afterhyperpolarization (sAHP), providing sustained, intrinsically generated negative feedback to neuronal excitation. Changes in the sAHP have been implicated in learning behaviors, in cognitive decline in aging, and in epileptogenesis...

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Detalles Bibliográficos
Autores principales: Tiwari, Manindra Nath, Mohan, Sandesh, Biala, Yoav, Yaari, Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947627/
https://www.ncbi.nlm.nih.gov/pubmed/29431274
http://dx.doi.org/10.1002/hipo.22836