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Crystal structure of an inferred ancestral bacterial pyruvate decarboxylase

Pyruvate decarboxylase (PDC; EC 4.1.1.1) is a key enzyme in homofermentative metabolism where ethanol is the major product. PDCs are thiamine pyrophosphate- and Mg(2+) ion-dependent enzymes that catalyse the non-oxidative decarboxylation of pyruvate to acetaldehyde and carbon dioxide. As this enzym...

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Detalles Bibliográficos
Autores principales:	Buddrus, Lisa, Andrews, Emma S. V., Leak, David J., Danson, Michael J., Arcus, Vickery L., Crennell, Susan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2018
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947705/ https://www.ncbi.nlm.nih.gov/pubmed/29497023 http://dx.doi.org/10.1107/S2053230X18002819

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