Crystal structure of an inferred ancestral bacterial pyruvate decarboxylase

Pyruvate decarboxylase (PDC; EC 4.1.1.1) is a key enzyme in homofermentative metabolism where ethanol is the major product. PDCs are thiamine pyrophos­phate- and Mg(2+) ion-dependent enzymes that catalyse the non-oxidative decarboxylation of pyruvate to acetaldehyde and carbon dioxide. As this enzym...

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Detalles Bibliográficos
Autores principales: Buddrus, Lisa, Andrews, Emma S. V., Leak, David J., Danson, Michael J., Arcus, Vickery L., Crennell, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947705/
https://www.ncbi.nlm.nih.gov/pubmed/29497023
http://dx.doi.org/10.1107/S2053230X18002819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947705/
https://www.ncbi.nlm.nih.gov/pubmed/29497023
http://dx.doi.org/10.1107/S2053230X18002819

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