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Ensembles generated from crystal structures of single distant homologues solve challenging molecular-replacement cases in AMPLE
Molecular replacement (MR) is the predominant route to solution of the phase problem in macromolecular crystallography. Although routine in many cases, it becomes more effortful and often impossible when the available experimental structures typically used as search models are only distantly homolog...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947759/ https://www.ncbi.nlm.nih.gov/pubmed/29533226 http://dx.doi.org/10.1107/S2059798318002310 |