Design of new anti-Alzheimer drugs: ring-expansion synthesis and synchrotron X-ray diffraction study of dimethyl 4-ethyl-11-fluoro-1,4,5,6,7,8-hexa­hydro­azonino[5,6-b]indole-2,3-di­carboxyl­ate

The title compound, C(20)H(23)FN(2)O(4), is the product of a ring-expansion reaction from a seven-membered fluorinated hexa­hydro­azepine to a nine-membered azonine. The nine-membered azonine ring of the mol­ecule adopts a chair–boat conformation. The C=C and C—N bond lengths [1.366 (3) and 1.407 (3...

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Detalles Bibliográficos
Autores principales: Toze, Flavien A. A., Listratova, Anna V., Voskressensky, Leonid G., Chernikova, Natalia Yu., Lobanov, Nikolai N., Bilyachenko, Alexey N., Dorovatovskii, Pavel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947790/
https://www.ncbi.nlm.nih.gov/pubmed/29765710
http://dx.doi.org/10.1107/S2056989018001329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947790/
https://www.ncbi.nlm.nih.gov/pubmed/29765710
http://dx.doi.org/10.1107/S2056989018001329

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