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KAP1 Regulates Regulatory T Cell Function and Proliferation in Both Foxp3-Dependent and -Independent Manners

Regulatory T cells (Tregs) are indispensable for the establishment of tolerance of self-antigens in animals. The transcriptional regulator Foxp3 is critical for Treg development and function, controlling the expression of genes important for Tregs through interactions with binding partners. We previ...

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Detalles Bibliográficos
Autores principales: Tanaka, Shigeru, Pfleger, Christian, Lai, Jen-Feng, Roan, Florence, Sun, Shao-Cong, Ziegler, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947873/
https://www.ncbi.nlm.nih.gov/pubmed/29669285
http://dx.doi.org/10.1016/j.celrep.2018.03.099